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Original Article
The diagnostic significance of APR score in early detection of neonatal bacterial infection.
Ki Won Park, Kyeong Choi, Young Youn Choi, Tai Ju Hwang
Clin Exp Pediatr. 1991;34(9):1223-1230.   Published online September 30, 1991
An accurate and rapid diagnostic test is essential in the management of bacterial infection in neonates because they lack specific symptoms and the bacterial infections in neonates tends to have rapid progression and poor prognosis. As for the method, APR (acute phase reactants), a score measuring C-reactive protein (CRP), 상racid glycoprotein (이-AG) and Haptoglobin (Hp) by latex agglutination seems to be one of promising methods. In...
Three cases of nonimmune hydrops fetalis.
Young Youn Choi, Jae Sook Ma, Tai Ju Hwang, Tae Bok Song
Clin Exp Pediatr. 1991;34(5):691-699.   Published online May 31, 1991
Nonimmune hydrops fetalis is defined as a pathologic and generalized abnormal accumulation of serous fluid in the entire body tissues and cavities unassociated with erythroblastosis. After the licensing of Rh Immune Prophylaxis (1968), the incidence of classic erythroblastosis fetalis has declined dramatically but the proportion of nonimmune types has increased relatively. With increasing use of ultrasound as a part of routine obstetric care, fetal...
Clinical observation of small for gestational age.
Young Zong Oh, Cheol Hee Hwang, Young Youn Choi, Young Joung Woo, Tai Ju Hwang
Clin Exp Pediatr. 1991;34(1):41-48.   Published online January 31, 1991
Small for gestaional age (SGA) is an entity which we have been slow to recognize in both pediatrics and obstetrics, despite its common occurrence and rather dramatic clinical manifestations. The goal of this study is to be enable all physicians involved in perinatal medical care focus their attention on the fact that infants of the same size but very different gestational ages are...
Three cases of Lyphodystophia Centrifugalis Abdominalis Juvenilis.
Young Soo Chun, Byung Hee Kim, Young Youn Choi, Tai Ju Hwang
Clin Exp Pediatr. 1990;33(8):1148-1154.   Published online August 31, 1990
The Lipodystropia centrifugalis abdominalis juvenilis (LCAJ) is a skin disorder characterized by progressive, centrifugal loss of subcutaneous fat on inguinal and/or axillary region. The lesion has slightly red border and scaly change on it. But other skin manifestations or other organ involvements are not the feature of the disease. We have experienced 3 cases of LCAJ. They were 7 years 1 month old body,...
Blood Pressure Values of Primary, Middle and High School Children in Kwangju.
Jin Soo Choi, Ki Weon Park, Jae Sook Ma, Tai Ju Hwang
Clin Exp Pediatr. 1990;33(7):952-958.   Published online July 31, 1990
For the purpose of establishing normal reference values, the author measured blood pressure of 6, 221 school children (male 3,587, female 2,634) in Kwangju area using automatic noninvasive oscil- lometic method. Blood pressure increased as age and height increased. Distributions of systolic blood pressures were 101±7 mmHg (Mean±SD) in boys and 102±7mmHg (Mean±SD) in sgirls at age 7 and increased with a rate of 1,6...
Treatment of Congenital Pulmonary Arteriovenous Fistula with Therapeutic Embolization in a Child.
Byung Hee Kim, Young Soo Chun, Jin Soo Choi, Jae Sook Ma, Tai Ju Hwang, Jae Kyu Kim
Clin Exp Pediatr. 1990;33(6):835-841.   Published online June 30, 1990
Congential pulmonary arteriovenous fistula is an uncommon malformation which has an abnormal connection between the pulmonary capillary bed, in which venous blood in the pulmonary artery is shunted through the fistula into the pulmonary vein without exposure to alveolar air, enters the left heart, and results in systemic arterial unsaturation, polycythemia, cyanosis and clubbing. Death often results from cerebral abscess and rupture of the...
Preventive Effect of Single Dose Vitamin K for the Late Hemorrhagic Disease of Infancy.
Young Youn Choi, Hwa Il Kwag, Byung Hee Kim, Tai Ju Hwang
Clin Exp Pediatr. 1990;33(5):606-614.   Published online May 31, 1990
To evaluate the preventive effect of single dose vitamin K for the late hemorrhagic disease of infancy, hepaplastin test was carried out in 15 breast-fed and 12 formula-fed babies. Vitamin Ki lmg was injected immediately after the birth intramuscularly and the test was performed the 1st (before vitamin k administration), 3rd, 7th, 28th days of life and the end of the 2nd and...
Prognosis according to Etiology and Age at Diagnosis in Congenital Hypothyroidism.
Myoung Sook Nam, Young Jong Oh, Byung Hee Kim, Young Jong Woo, Young Youn Choi, Tai Ju Hwang
Clin Exp Pediatr. 1990;33(4):506-513.   Published online April 30, 1990
A retrospective study on patients with congenital hypothyroidism was undertaken. The following results were obtained from 17 patients, on whom follow up investigations were available. 1) Males outnumbered females. The etiologic classification revealed: thyroid agenesis (64.7%), dyshormonogenesis (23.5%), and ectopic thyroid (11.8%). 2) In two-thirds of cases the diagnosis were made under 1 year of age, with 23.5% of cases being diagnoses below 3 month and 41.2%...
Posterior Nasal Swab Culture in Normal Newborns by Feeding Method.
Young Youn Choi, Tai Ju Hwang, Jae Sook Ma, Kwang Ok Lee, Byung Hee Kim, Young Soo Chung, En Kyeong Bom, Too Yong Yoo
Clin Exp Pediatr. 1990;33(4):472-480.   Published online April 30, 1990
To evaluate the difference of normal flora between breast and formula-fed newborns, we performed quantitative posterior nasal swab culture in 21 breast-and 44 formula-fed newborns. Positive culture rates of total aerobes and total anaerobes were 100% and 98%, respecitively. Among the aerobes, positive culture rate was 100% in group B streptococcus, 98% in gram negative bacteria, 86% in staphylococcus aureus, 82% in staphylococcus epidermidis...
A case of Beckwith-Wiedemann Syndrome.
Jin Soo Choi, Byung Hee Kim, Young Soo Chon, Hwa Il Kwang, Young Youn Choi, Tai Ju Hwang
Clin Exp Pediatr. 1990;33(3):367-372.   Published online March 31, 1990
The Beckwith-Wiedemann syndrome (exomphalos-macroglossia-gigantism: E M G Syndrome) is characterized by the presence of a wide variety of anomalies such as omphalocele, muscular macroglossia, gigantism, neonatal hypoglycemia, cytomegaly of the adrenal fetal cortex, hyperplasia of gonadal interstitial cells, and hyperplastic visceromegaly, particularly of pancreas and kidneys. Other abnormalities may include hemihypertrophy, microcephaly and mental retardation, prominent occiput, facial flame nevus, neonatal polycythemia, and linear indentations...
Two Cases of Quintuplets.
Hwa Il Kwag, Kwang Ok Lee, Wan Lee, Young Youn Choi, Tai Ju Hwang
Clin Exp Pediatr. 1989;32(5):687-694.   Published online May 31, 1989
The incidence of multiple pregnancies is realtively low in humanbeing than in other species. The reported incidence of multiple pregnancies is highest among Blacks and East Indians, followed by North European White, and is lowest among the Mongolian races. Recently, with advent of clomiphen therapy, multple pregnancies are more freqently encountered. Multiple pregnancies are frequently associated with highest rate of maternal morbidities and pregnancy wastages...
A Case of Ectopic ACTH Syndrome Caused by Wilms Tumor.
Dong Hun Chi, Sang Bong Han, Young Jong Woo, Tai Ju Hwang
Clin Exp Pediatr. 1988;31(8):1071-1078.   Published online August 31, 1988
We experienced a extremely rare case of ectopic ACTH syndrome caused by Wilms tumor in a 4 year 8 month-old female patient. We performed specific radiologic and hormonal studies. Diagnosis was confirmed by histologic and biochemical findings of tumor mass after right nephrectomy. A brief review of related literature was made.
A Case of Left Atrial Myxoma in Childhood.
Heu Ran Min, Myoung Hee Kook, Yong Jong Woo, Jae Suk Ma, Tai Ju Hwang
Clin Exp Pediatr. 1988;31(2):263-270.   Published online February 28, 1988
Cardiac myxomas are rare in children. Because of their rarity and protean clinical manifestations, diagnosis is difficult but cardiac myxomas recently have generated a great deal of interest because they represent a potentially curable form of serious heart disease which can be diagnosed easily and accurately by echocardiography. We presented a case of left atrial myxoma in a 13-year old girl. The diagnosis was...
A Epidemiologic Study of Malignant Tumors of Children in Chonnam Area.
Myong Hee Kook, Hys Ran Min, Tai Ju Hwang
Clin Exp Pediatr. 1988;31(1):78-85.   Published online January 31, 1988
A Total 655 cases of malignant tumors in childhood under 15 years of age who admitted to general hospitals in Chonnam area during the 10-year period from January 1976 to December 1985 were analysed. The frequency of malignant tumors among total pediatric inpatients was 2.64% (1.48〜4.52%) with tendency to increse year after year. In 1980, the number of population under 15 years of age...
A Clinico-Epidemilological Study of 55 Cases of Chidhood Idiopathic Thrombocytopenic Purpura.
Won Ho Kang, Myung Hee Kook, Yong Sang Yoo, Jae Suk Ma, Tai Ju Hwang
Clin Exp Pediatr. 1987;30(11):1207-1212.   Published online November 30, 1987
Fifty-five children with idiopathic thrombocytopenic purpura (ITP) were admitted to the Department of pediatrics, Chonnam University Hospital during 6 years and 5 months from January 1980 to May 1986. We Compared clinical pictures and effects of steroids and platelet concentrates on acute and chronic ITP. No significant sexual predominance was found in total patients with ITP, but also between acute and chronic types,...
Results of Treatment in Children with Acute Lymphocytic Leukemia.
Saeng Gu Cho, Tai Ju Hwang
Clin Exp Pediatr. 1986;29(12):1343-1351.   Published online December 31, 1986
The clinical findings on the 1st examination in 70 patients who were admitted to the pediatric department of Chonnam University Hospital from January, 1977 to January, 1985 as well as the results of treatment in 32 patients were analyzed. The most frequent age at onset was 4-5 years(15 patients). Male patients outnumbered female patients by 1.6 : 1. A mediastinal mass and...
A Case of Glanzmann's Thrombathenia.
Saeng Gu Cho, Won Ho Kang, Young Youn Choi, Tai Ju Hwang, Dong Wook Ryang, Joo Young Yoo
Clin Exp Pediatr. 1986;29(6):668-673.   Published online June 30, 1986
The authors experienced a 6-year-old female patient with Glanzmann’s Thrombathenia and cerebral palsy. She was admitted with epistaxis, gingival bleeding and easy bruisability. Platelets of patients showed complete absence of aggreration in response to ADP, collagen, and epinephrine but only first aggregation to ristocetin. After platelet aggregation test, bone marrow aspiration, and electron micrographic examination, she was proved as...
Methodology of Cancer Cell Culture and it's Clinical Application.
Tai Ju Hwang
Clin Exp Pediatr. 1986;29(5):479-486.   Published online May 31, 1986
Case Report
A Case of Fatal Intracranial Hemmrhage due to Vitamin K Deficiency.
Yong Sang Yoo, Moon Tae Jeong, Jai Sook Ma, Tai Ju Hwang
Clin Exp Pediatr. 1986;29(1):108-112.   Published online January 31, 1986
The authors experienced a case of massive spontaneous intracranial hemorrhage in anotherwise healthy 21-day-old breast fed male infant. There were no evidences of external trauma. Coagulation studies showed marked prolongation of prothrombin time and partial thromboplastin time. They were significantly corrected after vitamin K administration without clinical improvsment. We concluded that vitamin K deficiency was accounted for the pathogenesis of fatal...
A Case of Kocher-Debre-Semelaigne Syndrome.
Saeng Gu Cho, Song Tae Kim, Young Youn Choi, Tai Ju Hwang
Clin Exp Pediatr. 1985;28(11):1130-1135.   Published online November 30, 1985
The authors experienced a 9-year-old male patient with Kocher-Decre-Semelaigne syndrome, hypothyroidism with generalized muscular hypertrophy. He was admitted with puffy face, abdominal distension, retarded growth, mental retardation, generalized muscular hypertrophy and hypertonia. Thyroid function test revealed hypofunction and thyroid gland was not visualized by 99raTc scintiscan. The stigmas of hypothyroidism and the muscular hypertrophy disappeared promptly after synthyroid replacement. Muscular biopsy...
Original Article
Early Reduction of Serum Amylase Activity in Children with Epidemic Encephalitis.
Suk Jung Chang, Eui Hyung Kim, Tai Ju Hwang, Chull Sohn
Clin Exp Pediatr. 1984;27(4):350-357.   Published online April 30, 1984
In 52 children aged form 5 to 13 years who were acutely starving from epidemic encephalitis, authors measured the level of amylase activity, BUN, GOT, GPT, alkaline phosphatase, total protein, albumin, globulin, creatinine in serum and GOT, GPT, amylase activity in CSF. And in another group of 7 children with acute viral hepatitis, GOT, GPT in serum and CSF were...
Serum and Urine Zinc Values in Infectious Diseases.
Yong Tai Suh, Hwa Young Kim, Jai Sook Mah, Tai Ju Hwang
Clin Exp Pediatr. 1984;27(3):237-245.   Published online March 31, 1984
Using atomic absorption spectrophotometer, serum-and urine zinc levels of healthy children aging 4.7 to 6.9 years, and of various infectious diseases, including acute viral hepatitis， tuberculosis, salmonellosis, and shigellosis were determined. The mean zinc levels in healthy children were 76±15.2^g/100 ml in serum and 275土 142.4/ug/L in urine respectively. There was no statistical difference attributable to sex. No remarkable changes...
Case Report
A Case of Congenital Hypoplastic Anemia.
Young Jong Woo, Jae Sook Ma, Tai Ju Hwang
Clin Exp Pediatr. 1983;26(2):188-192.   Published online February 28, 1983
Authors have observed a case of congenital hypoplastic anemia in 18 months old male patient who was diagnosed through the bone marrow aspiration. The liver was enlarged and the biopsy specimen disclosed iron deposition in the hepatocyte, which was thought to be resulted from multiple blood transfusion and administration of iron preparation. A brief review of related literature was made.
A Case of Congenital Biliary Atresia associated with Ectopic Pancreatic Tissue.
Hyung Chun Kim, Tai Ju Hwang, Kyung Yong Huh
Clin Exp Pediatr. 1980;23(9):737-740.   Published online September 15, 1980
Congenital biliary atresia is the commonest cause of prolonged obstructive jaundice in the neonatal period, and is due to the pathologic closure of a major portion or segment of the biliary tree. The neonate with prolonged obstructive jaundice poses a diagnostic dilemma that may be insoluble by routine clinical and laboratory studies. This applies particularly to the most common entities,...
Original Article
Effects of the Cyclophosphamide and 6-Mercaptopurine on the RES Function in Rats.
Tai Ju Hwang, Hyung Chun Kim
Clin Exp Pediatr. 1980;23(7):521-526.   Published online July 15, 1980
To study the effect of anticancer drugs on the RESFunction, cyclophosphamide and 6-mercaptopurine were intramuscularly injected and evaluated the reticuloendotherial phagocytic activity by the carbon clearence method in rats. Experimental groups were subdivided by the dosage, into the small and large dosage groups, and by the duration of treatment, into the 1, 3, 5 days and 8days (3 days cessation...
Clinical Studies on Purpura in Children.
Hyo Duck Kim, Tai Ju Hwang, Jung Hi Oh
Clin Exp Pediatr. 1979;22(11):977-984.   Published online November 15, 1979
The following results were obtained through the clinical review of 182 cases who were admitted with purpuric manifestation at the Pediatric Department of Chonnam National University Hospital during the four-year period, January 1975 through Decemver 1978. 1. The incidence was in the order of leukemia 50 cases(27.5%), sepsis 33 cases(18.1%), meningococcemia 33 cases(18.1%), allergic purpura 29 cases(15.9%), aplastic anemia 19...
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